From Sonora: take 49 into Jackson, drive through Jackson, take 49 exit to Sutter Creek on right, turn right at the third stoplight to drive through Sutter Creek and continue 2 miles to Amador City. Driving time from Sonora: about 1 hour.
From Lake Tahoe: North Shore – can go either 80 to Auburn to 49 to Placerville (very winding) or 80 to Sacramento to 50 to 16 to Jackson. South Shore – 50 to Placerville to 49, or 89 to 88 down past Kirkwood to Jackson to 49. Driving time: South Shore – about 2 hours. Truckee: 2 hours 45 minutes.
From Kirkwood: 88 south to Jackson, then 49 to turn off on right to Sutter Creek and on to Amador City. Driving time: 1 hour 15 minutes (weather and ski traffic dependent).